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ADOLESCENT TYPE 1 DIABETES CARDIO-RENAL INTERVENTION TRIAL

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AdDIT Publications

1. Marcovecchio ML, Chiesa ST, Armitage J, Daneman D, Donaghue KC, Jones TW, Mahmud FH, Marshall SM, Neil HAW, Dalton RN, Deanfield J, Dunger DB; Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT) Study  Group. Renal and Cardiovascular Risk According to Tertiles of Urinary Albumin-to Creatinine Ratio: The Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT). Diabetes Care. 2018 Sep;41(9):1963-1969. doi: 10.2337/dc18-1125. Epub 2018 Jul 19.

PubMed Link

2. Marcovecchio ML, Chiesa ST, Bond S, Daneman D, Dawson S, Donaghue KC, Jones TW, Mahmud FH, Marshall SM, Neil HAW, Dalton RN, Deanfield J, Dunger DB; AdDIT Study Group. ACE Inhibitors and Statins in Adolescents with Type 1 Diabetes. N Engl J Med.2017 Nov 2;377(18):1733-1745.

PubMed Link

3. Adolescent type 1 Diabetes cardio-renal Intervention Trial Research Group. Adolescent type 1 Diabetes Cardio-renal Intervention Trial (AdDIT). BMC Paediatric 2009; 9:17.

PubMed Link 

4. Marcovecchio ML, Woodside J, Jones T, Daneman D, Neil A, Prevost T, et al. Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT): urinary screening and baseline biochemical and cardiovascular assessments. Diabetes Care. 2014; 37:805-13.

PubMed Link

5. Cherney DZ, Scholey JW, Daneman D, Dunger DB, Dalton RN, Moineddin R, et al. Urinary markers of renal inflammation in adolescents with Type 1 diabetes mellitus and normoalbuminuria. Diabetic medicine: a journal of the British Diabetic Association. 2012; 29:1297-302.

PubMed Link

6. Har RL, Reich HN, Scholey JW, Daneman D, Dunger DB, Moineddin R, et al. The urinary cytokine/chemokine signature of renal hyperfiltration in adolescents with type 1 diabetes. PLoS One. 2014; 9:e111131.

PubMed Link

7. Maftei O, Pena AS, Sullivan T, Jones TW, Donaghue KC, Cameron FJ, et al. Early atherosclerosis relates to urinary albumin excretion and cardiovascular risk factors in adolescents with type 1 diabetes: Adolescent type 1 Diabetes cardio-renal Intervention Trial (AdDIT). Diabetes Care. 2014; 37:3069-75.

PubMed Link

8. Cho YH, Craig ME, Davis EA, Cotterill AM, Couper JJ, Cameron FJ, et al. Cardiac autonomic dysfunction is associated with high-risk albumin-to-creatinine ratio in young adolescents with type 1 diabetes in AdDIT (adolescent type 1 diabetes cardio-renal interventional trial). Diabetes Care. 2015; 38:676-81.

PubMed Link

9. Lytvyn Y, Mahmud FH, Daneman D, Deda L, Dunger DB, Deanfield J, et al. Association Between Plasma Uric Acid Levels and Cardiorenal Function in Adolescents With Type 1 Diabetes. Diabetes Care. 2016; 39:611-6.

PubMed Link

10. Inman M, Daneman D, Curtis J, Sochett E, Clarke A, Dunger DB, et al. Social Determinants of Health Are Associated with Modifiable Risk Factors for Cardiovascular Disease and Vascular Function in Pediatric Type 1 Diabetes. J Pediatr. 2016; 177:167-72.

PubMed Link

11. Inman M, Daneman D, Curtis J, Sochett E, Elia Y, Dunger DB, et al. Assessing social determinants of health in a pediatric diabetes clinical research trial: Are recruited subjects representative of the larger clinical population? Diabetes research and clinical practice. 2016; 113:41-3.

PubMed Link

12. Bradley TJ, Slorach C, Mahmud FH, Dunger DB, Deanfield J, Deda L, et al. Early changes in cardiovascular structure and function in adolescents with type 1 diabetes. Cardiovasc Diabetol. 2016; 15:31.

PubMed Link

13. Dunger DB. Banting Memorial Lecture 2016 Reducing lifetime risk of complications in adolescents with Type 1 diabetes. Diabet Med. 2017 Apr;34(4):460-466

PubMed Link

14. Burns KD, Lytvyn Y, Mahmud FH, Daneman D, Deda L, Dunger DB, et al. The Relationship between Urinary Renin Angiotensin System Markers, Renal and Vascular Function in Adolescents with Type 1 Diabetes. Am J Physiol Renal Physiol. 2017 Feb 1;312(2):F335-F342

PubMed Link

15. Benitez-Aguirre PZ, Wong TY, Craig ME, Davis EA, Cotterill A, Couper JJ, Cameron FJ, Mahmud FH, Jones TW, Hodgson LAB, Dalton RN, Dunger DB, Donaghue KC; Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT). The Adolescent Cardio-Renal Intervention Trial (AdDIT): retinal vascular geometry and renal function in adolescents with type 1 diabetes. Diabetologia. 2018 Apr;61(4):968-976.

PubMed Link

16. Lovshin JA, Škrtić M, Bjornstad P, Moineddin R, Daneman D, Dunger D, Reich HN, Mahmud FH, Scholey JW, I Cherney DZ, Sochett EB. Hyperfiltration, urinary albumin excretion, and ambulatory blood pressure in adolescents with type 1 diabetes mellitus. Am J Physiol Renal Physiol. 2018 Apr 1;314(4):F667-F674. doi: 10.1152/ajprenal.00400.2017. Epub 2017 Dec 13.

PubMed Link

17. Cummings LAM, Clarke A, Sochett E, Daneman D, Cherney DZ, Reich HN, Scholey JW, Dunger DB, Mahmud FH. Social Determinants of Health Are Associated with Markers of Renal Injury in Adolescents with Type 1 Diabetes. J Pediatr. 2018 Jul;198:247-253.e1

PubMed Link

18. Chiesa ST, Charakida M, McLoughlin E, Nguyen HC, Georgiopoulos G, Motran L, Elia Y, Marcovecchio ML, Dunger DB, Dalton RN, Daneman D, Sochett E, Mahmud FH, Deanfield. JE. Elevated high-density lipoprotein in adolescents with type 1 diabetes is associated with endothelial dysfunction in the presence of systemic inflammation. Eur Heart J. 2019 Mar 12. pii: ehz114. doi: 10.1093/eurheartj/ehz114. [Epub ahead of print]

PubMed Link

19. Dunger DB, Marcovecchio ML, Deanfield J. ACE Inhibitors and Statins in Adolescents with Type 1 Diabetes. N Engl J Med. 2018 Feb 8;378(6):580-581

20. Dunger DB, Ashford J, Marcovecchio L. Albumin excretion in adolescents with diabetes. J Renal Nurs 2014;6:5.

21. Marcovecchio ML, Dunger DB. Evaluating cardio-renal protection for adolescents with type 1 diabetes: the current AdDIT trial. Practical Diabetes 2012;29:1-3.

22. Marcovecchio ML, Dunger D. Can increased albumin excretion provide evidence of early renal and cardiovascular disease in adolescents with type 1 diabetes? Diabetes Management 2014;4:227-230.

 

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